joe rogan dr rhonda patrick vitamin d

And there's been some. That's interesting because my friend Michael, who got it, his mom who got it, who's in her 70s, is Asian, and that is she kicked it. It's also the region that that is used to get inside of the cell. So our sauna is like it's pretty small. There's another meta analysis that looked at two hundred milligrams up to like 200 milligrams, up to two grams. We have this whole. Hmm. Now it's like, you know, did you realize how much work being a mom was for you? You know, I don't you know, I'm not sure. Normally it goes to your liver and it's involved in blood coagulation, but when there's enough vitamin K one around, it stays in the periphery and it moves calcium periphery being bloodstream it calcium out of the bloodstream and takes it to places where it's supposed to go like the bones in the muscle. Do you, do you do like electrolyte replenishment. So so this is like there's one thing that it's important to keep in mind when we say asymptomatic, like, you know, there's asymptomatic and like a person that never actually gets symptoms. I was terrified and it thankfully has not been that bad. And oftentimes these vaccine studies are used to kind of test the immune response and like how you're how robust your immune response is because you're you're given a vaccine and there's all different types of vaccines, you know, pieces of an antigen or different types of, you know, ways that you can you can expose someone to a bacteria or virus, but you have a response to it. So it's not like full stop. It's a two person sauna and. That's what I mean. Yeah. Yeah, yeah. Yeah, let's definitely talk more. You know, or they just that they're so fucked up by the time they get on a ventilator, they just want to dying. You know, they're kind slower, a little more decrepit. That is just it is a game like I'm so much more relaxed and this is like I think I've told you the story. Right. And, you know, part of that, an adaptive immune response is, you know, to produce antibodies. I get a flare up and it's like I'm sure I'm out. To get an outcome. So it stretches the spine out and decompresses it and it gives you a lot of relief. Yeah. So. You can't manage that, right? If anyone can do that study, amazing. I remember I was on a plane once and there was this guy behind me and he was a kind of a heavy fellow and he was, he was really snoring loud. That's how I first got in that one of my first biological experiments ever because I was a chemistry major in college. Month to month and a half or whatever, and we kind of like my team and I just drove in and put together an article, released a podcast on it, a video where we just kind of covered everything. It is a known fact protein will bind to this vitamin. I mean, I'm wearing it because I'm sort of trying to understand how different foods have different lifestyle changes, like how long you've been wearing it. Kevin Rose tells me I can take my Apple Watch and the hot frickin and do it right. So he gets in over two hundred degrees with a fucking aerodyne bike with oven mitts on this crazy asshole is riding in Aerodyne. I will say this like my one of my friends, she's a she's an M.D. What about an advanced health care directive and what's a power of attorney? I was just in this dark little apartment and, you know, like it just it wasn't really great for my circadian rhythm because I would wake up in the morning, especially like on weekends and stuff like, you know, there's like no. It's kind of like you read these stories. And they have fantastic grub's. Her podcasts and other videos can be found at FoundMyFitness.com Yeah. No, no, no. I must be a little bit on the spectrum because I could swear OP's title doesn't say a damn thing about Rhonda figuring this out. Healthy Fats, RELATED: Joe Rogans Diet & Workout Routine. I'll show how it works before. Yes, YouTube channel found my fitness and a website found my fitness and found my fitness Instagram. But like, I know that it's going to help with muscle atrophy. Oh, can I, can I exploit rock pools. You know, it's well, it's it's important. I'm sorry. I think it's going to be once a week. I love it. Eveillard too much. Jesus Christ. I got a mouthpiece and it's amazing. But I got addicted to it. Yeah, it's really it's so horrible. Like there was a time when I would you know, like I lived in in Oakland. Or if you if you really want to, you could wear a towel like if you were modest or whatever, because to them it's like, oh no big deal. Or does the is are you required to you know, different people have different results when it comes to CBD and some people find that CBD with THC benefits some more and some people find that it's just the CBD itself. It shows you like really accurate sleep. After hot yoga. You're going to be paying a lot out, but you got to 220. But you do you do sweat out certain compounds like aluminum, aluminum, like it's funny that you can actually excrete certain compounds better from sweat than urine, because that's another way of eliminating things through urine. Yeah. I don't know. I've got two publications on it. Visit trigger grills dotcom. I mean, it's like naptime is like what can I get work done or it could take a shower. I don't I don't have that same perspective. And so I just started pouring water on, on the thing. I also had a gym I was going to for. So he was like, got it. I know. Check out these Podcast Notes from Rhonda's last appearance on Joe's podcast; BPA. So so my doctor might see my dentist is great because he like, you know, any dentist could just be like, no, they're still there. I don't I'm not as concerned. Since the measurements for certain geographies are in nmol/L, conversions can easily be reached using an online units calculator. Like saying in 104, that's that's pretty hot. Right. Well, he was in Tarzana. Like, my Mother-In-Law has to go. I'm definitely not going to do it the way it was before. It might be coming out. Also, not sure it takes much of a genius to figure this out, at least in the sense that no sun = no vitamin D = issues. Like, why can't you wear a swimsuit? The weights are actually behind you and it carries you carrying all the weight on your hips, which strengthens the legs without putting a load on the back, which is fantastic. Vitamin D is then converted by the body into calcitriol, a steroid hormone. But that's interesting because your neutrophils, your neutrophils generate hydrogen peroxide. So we had like one of the Britain girls like and she was like, I mean it was just like, here's the here's the truth. It's like so taxing. First of all, you can do it with no weight. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc. Yeah. I certainly like, you know, you said so, you know, take that with a grain of salt as well. So monoclonal antibodies, I think, are a really big, you know, possibility for a promising therapeutic because you can then I mean, the problem is growing like large scale manufacturing them. That's been shown it's given them a cardiovascular workout without having to force them to go for a run down a bike. These are people that really have no business telling you what to do and what not to do. I forget all of this stuff. So but she's going to measure the effects on on, you know, on depressed patients. You're not making vitamin D. Also, if you have darker skin, melanin protects you like the whole, you know, people with darker skin, people from maybe Africa or India or South Asia, the more equatorial regions, they're closer, you know, closer to to to the equator. And so but that's what you want is like the combination. And this was like a big problem for the RSV vaccine back in the you know, like most kids get RSV, it's a respiratory tract infection. I mean, the things that are like, ironic. I was trying not to look at everyone, you know, like I didn't want to see, like, you know, married, like, I don't want stuff. But anyways, it was my first time camping, like outside, like not in like like I've been to Yosemite, but I like staying in a cabin. It's going to create carbon and it's going to create more life forms. But the thing is, is that there is adaptation that happens. You know, it'll be interesting to see the data from those trials, whether or not there's going to be an effect, it's not known. But they were all naked, like it was like I guess Europeans are like that, you know, like they're more used to it or that's what someone was telling me. Yeah, I was doing. But I mean, I think there's so many things there's just there's so many factors that a lot of data that needs to be passed out for sure. And and then just more and more studies came out where it was not not only not helpful, it was, you know, toxic. And they found with influenza, I forgot which a or something. So so there are people that have variations in genes that cause them to genetically have lower vitamin D. And so this this is called Mendelian randomisation, where you can take a person that's that has a genetically like it's they're genetically low vitamin D, so you're not categorizing them based on their vitamin D levels. Well, in the in the. It lowered the incidence of the solutions in the children because, you know, mothers kiss their kids and they transferred oral bacteria. Like, if you were having a discussion with a good friend and the good friend was looking at something that you said and said, I disagree because of this. And we're brought to you by legal zoom. Yeah, for Jamie, can you pull up filmi fitness and there's a vitamin C topic page so that we I can answer that question better because there's just there's a graph if you just like scroll to the graph, there's like all this is on your website, which tell everybody I found my fitness dotcom vitamin C or episode page of the podcast. I mean like not being able to breathe. And bone density. You really need to find someone who's willing to go. So yeah. There is a possibility supplementing with vitamin D can decrease the severity of the COVID-19 infection and eliminate the need for hospitalization.

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